Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980377 | 0.69 | CES2 (0.38) | KMT2A | |
| SCHEMBL5713331 | 0.67 | ALDH1A1 (0.55) | FLT1KDRMAOBKDM4EALDH1A1 | |
| SCHEMBL2316007 | 0.66 | TAAR1 (0.57) | MAOBNR3C2TAAR1IDO1HDAC1 | |
| SCHEMBL5983327 | 0.65 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TAAR1 | |
| SCHEMBL934147 | 0.65 | HDAC1 (0.57) | MAOBNR3C2TAAR1IDO1HDAC1 | |
| SCHEMBL22190365 | 0.64 | TAAR1 (0.50) | MAOBNR3C2TAAR1IDO1HDAC1 | |
| SCHEMBL14973107 | 0.64 | KDM4E (0.43) | FLT1KDRMAOBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28626980 | 0.64 | SIRT2 (0.44) | MAOBSMN1; SMN2TAAR1IDO1DAO | |
| SCHEMBL25138775 | 0.64 | HDAC1 (0.59) | MAOBNR3C2TAAR1IDO1HDAC1 | |
| Hydrochloric Acid SCHEMBL30882461 | 0.64 | HDAC1 (0.55) | MAOBNR3C2TAAR1IDO1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940802-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Pfizer Products Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007034326-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |