Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998742 | 0.83 | LMNA (0.52) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL4949823 | 0.82 | ACACB (0.38) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL27956164 | 0.82 | POLB (0.42) | TSHRLIPEBCHEPLAURORC | |
| SCHEMBL27956181 | 0.82 | ALDH1A1 (0.38) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL3384800 | 0.81 | LIPE (0.35) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL27406467 | 0.81 | TSHR (0.41) | TSHRPLAURORCKDM4E | |
| SCHEMBL4537672 | 0.80 | LMNA (0.49) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL10435485 | 0.78 | L3MBTL1 (0.46) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL16322862 | 0.77 | MAPT (0.39) | LMNAMAPK1KMT2A | |
| SCHEMBL4537676 | 0.76 | L3MBTL1 (0.49) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502237-A | FAAH inhibitors | IRONWOOD PHARMACEUTICALS INC | 2014-01-08 | — | — | CN | disclosed |
| EP-1958946-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| CN-1281591-C | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1416419-A | 4-aminopyridinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2003-05-07 | — | — | CN | disclosed |