Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950547 | 0.85 | TDP1 (0.47) | XDHGRM5ROCK2ROCK1 | |
| SCHEMBL4950448 | 0.84 | ALDH1A1 (0.40) | SLC22A12GSK3BMAPTGSK3A | |
| SCHEMBL27724211 | 0.81 | CYP17A1 (0.43) | GSK3BMAPTROCK2GSK3A | |
| SCHEMBL4949007 | 0.80 | GRM5 (0.36) | XDHSCN5ASCN9AGRM5ROCK2 | |
| SCHEMBL4950379 | 0.78 | SCN9A (0.37) | XDHSCN5ASCN9AGRM5 | |
| SCHEMBL4953795 | 0.77 | TDP1 (0.47) | XDH | |
| SCHEMBL8164711 | 0.74 | GRIA4 (0.67) | SCN5ASCN9AGRM5ROCK2ROCK1 | |
| SCHEMBL3828607 | 0.74 | GRIA4 (0.67) | SCN5ASCN9AGRM5ROCK2ROCK1 | |
| SCHEMBL15507351 | 0.72 | MAP4K4 (0.49) | XDHSLC22A12GPR119 | |
| SCHEMBL28571512 | 0.72 | XDH (0.48) | XDHSLC22A12GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |