Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.53 |
| ▸ | FYN | P06241 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624516 | 0.84 | CYP1A2 (0.58) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL18600577 | 0.80 | TRPM4 (0.68) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL16200914 | 0.79 | TRPM4 (0.55) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL27760500 | 0.78 | TRPM4 (0.65) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL25622486 | 0.78 | TRPM4 (0.59) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL598916 | 0.78 | ALDH1A1 (0.60) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL4949723 | 0.76 | CYP1A2 (0.49) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL19915326 | 0.76 | CYP1A2 (0.57) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL16107767 | 0.76 | TRPM4 (0.61) | CYP1A2FYNACHEAHRERBB2 | |
| SCHEMBL7996318 | 0.76 | CYP1A2 (0.67) | CYP1A2FYNACHEAHRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557565-B2 | Degradation of polycyclic aromatic hydrocarbons to render them available for biodegradation | WAVREK DAVID (US) | 2013-10-15 | — | — | US | disclosed |
| US-8298814-B1 | Degradation of polycyclic aromatic hydrocarbons | Wavrek, David A. (US) | 2012-10-30 | — | — | US | disclosed |
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | HONG P K ANDY | 2008-10-02 | — | — | US | disclosed |
| EP-1230400-B1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIV UTAH RES FOUND (US) | 2008-09-24 | — | — | EP | disclosed |
| EP-1230400-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | University of Utah Research Foundation (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032936-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | PAH, AHR, TDO2 | CYP1A2 91/4885FYN 2324/4885ACHE 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.