Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889884 | 1.00 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE | |
| SCHEMBL7661200 | 1.00 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE | |
| SCHEMBL49680 | 1.00 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE | |
| SCHEMBL16424434 | 0.97 | TDP1 (0.63) | TDP1CYP3A4ESR1ESR2ACHE | |
| P-Xylene SCHEMBL10884475 | 0.97 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2ACHE | |
| P-Xylene SCHEMBL11109973 | 0.94 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE | |
| P-Xylene SCHEMBL11108935 | 0.94 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE | |
| Toluene SCHEMBL6561280 | 0.92 | TDP1 (0.71) | TDP1CYP3A4ESR1ESR2ACHE | |
| SCHEMBL9115203 | 0.91 | ESR1 (0.56) | TDP1CYP3A4ESR1ESR2ACHE | |
| Toluene SCHEMBL25365395 | 0.89 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689847-B | Preparation method of aryl propionic acid compound | 浙江新和成股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-108003092-B | Synthetic method of 2, 3-dichloropyridine | 重庆中邦科技有限公司 | 2021-04-02 | — | — | CN | claimed |
| CN-111689847-B | Preparation method of aryl propionic acid compound | 浙江新和成股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| CN-108003092-B | Synthetic method of 2, 3-dichloropyridine | 重庆中邦科技有限公司 | 2021-04-02 | — | — | CN | disclosed |
| US-10454042-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2019-10-22 | — | — | US | disclosed |
| WO-2019109143-A1 | HEAVY-METAL-FREE METAL CHALCOGENIDE NANOPLATELETS | CURTIN UNIVERSITY (AU) | 2019-06-13 | — | — | WO | disclosed |
| EP-2970074-B1 | HYDROFORMYLATION PROVESS USING A HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-20180244865-A1 | INCREASED EFFICIENCY DESULFURIZATION REAGENTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-08-30 | — | — | US | disclosed |
| EP-3341432-A1 | INCREASED EFFICIENCY DESULFURIZATION REAGENTS | ARLANXEO Deutschland GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-10010879-B2 | Phosphine triply cross-linked by organic polymer, transition metal complex using said phosphine as a ligand, and catalyst | TOSOH ORGANIC CHEMICAL CO., LTD (JP) | 2018-07-03 | — | — | US | disclosed |
| WO-1999001461-A1 | PRODUCTION OF ALKALI METAL DIARYLPHOSPHIDE AND CYCLOALKYLDIARYLPHOSPHINES | ALBEMARLE CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
| US-5777169-A | Production of high purity alkali metal diarylphosphide and cycloalkyldiarylphosphines | ALBEMARLE CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5414160-A | Use of dimerization catalyst formed in situ from organonickel compound with no nickel-halogen bond, triarylphosphine and/or monoalkyldiarylphosphine, organoaluminum compound, hydrogen; hydroformylation and hydrogenation of dimer to alcohols | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-09 | — | — | US | disclosed |
| US-4892954-A | REACTION OF EPOXY COMPOUNDS AND CARBON DIOXIDE, BASIC CATALYST | HOECHST AG (DE) | 1990-01-09 | — | — | US | disclosed |
| US-4661623-A | CATALYST SELECTIVITY | ASHLAND OIL, INC. (US) | 1987-04-28 | — | — | US | disclosed |
| US-4599456-A | STORAGE STABILITY | PHILLIPS PETROLEUM COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4257973-A | USING ORGANOPHOSPHORUS-PALLADIUM HALIDE COORDINATION CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4007123-A | PHOSPHATE, POLYALKYLENE GLYCOL AND AN ORGANO-SELENIUM OR TELLURIUM | MCDONNELL DOUGLAS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-4001129-A | PHOSPHATE ESTER, POLYETHER, DICARBOXYLIC ACID ESTER, SELENIDES, TELLURIDES, HYDRAULIC FLUIDS | MCDONNELL DOUGLAS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010879-B2 | Phosphine triply cross-linked by organic polymer, transition metal complex using said phosphine as a ligand, and catalyst | PHOSPHO1, PTDSS1, PLTP | TDP1 3091/4885CYP3A4 1269/4885ESR1 1839/4885 |
| US-10454042-B2 | Organic electroluminescence device | EML4, ELOC, ORC3 | TDP1 2483/4885CYP3A4 477/4885ESR1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.