Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006072 | 0.84 | ESR2 (0.36) | MAPT | |
| SCHEMBL5244034 | 0.73 | HSD11B1 (0.41) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL5824341 | 0.70 | OPRM1 (0.47) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL1005980 | 0.67 | ESR2 (0.40) | — | |
| SCHEMBL21724095 | 0.67 | SLC6A3 (0.41) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7113263 | 0.67 | SLC6A3 (0.41) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL725435 | 0.66 | ALDH1A1 (0.43) | MEN1KMT2ATSHRHTR2AMAPT | |
| SCHEMBL1823422 | 0.66 | HSD11B1 (0.36) | MEN1KMT2ATSHRHTR2AHTR2C | |
| SCHEMBL10779647 | 0.65 | MEN1 (0.42) | MEN1KMT2ATSHRHTR2AHTR2C | |
| SCHEMBL4639315 | 0.64 | HSD11B1 (0.44) | ALDH1A1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021135-A2 | SYNERETIC COMPOSITION, ASSOCIATED METHOD AND ARTICLE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008019149-A1 | COMPOSITION AND ASSOCIATED METHOD | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-02-14 | — | — | WO | disclosed |