Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617070 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL4948450 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL30874619 | 0.75 | NOS1 (0.35) | NOS1NOS3NOS2 | |
| SCHEMBL3393447 | 0.71 | CYP2D6 (0.33) | — | |
| SCHEMBL674128 | 0.69 | CPB1 (0.34) | NOS1NOS3NOS2 | |
| SCHEMBL29086267 | 0.69 | CPB1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL617763 | 0.69 | KMT2A (0.34) | NOS1NOS3NOS2 | |
| Acetic Acid SCHEMBL9715511 | 0.68 | GABRR1 (0.39) | GABRR1 | |
| SCHEMBL28841424 | 0.68 | CTH (0.34) | GABRR1 | |
| SCHEMBL30831230 | 0.68 | NOS1 (0.30) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618195-B1 | METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND SENSE PEPPTIDO-NUCLEIC ACIDS (PNA) | UNIV BOLOGNA ALMA MATER (IT) | 2008-03-12 | — | — | EP | disclosed |
| US-20070020632-A1 | Method for selective inhibition of human n-myc gene in n-myc expressing tumors through antisense and antigen peptido-nucleic acids (pna) | BIOGENERA S.P.A. (IT) | 2007-01-25 | — | — | US | disclosed |
| EP-1618195-A2 | METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) | UNIVERSITA DEGLI STUDI DI BOLOGNA (IT) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004096826-A2 | METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) | UNIVERSITA' DEGLI STUDI DI BOLOGNA (IT) | 2004-11-11 | — | — | WO | disclosed |