Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951358 | 0.89 | ABCC4 (0.41) | LMNAKDM4ETSHRMAPK8MAPK10 | |
| SCHEMBL4951060 | 0.82 | NPSR1 (0.44) | CA2 | |
| SCHEMBL4953693 | 0.80 | GRIA4 (0.49) | KDM4ECA2 | |
| SCHEMBL4953413 | 0.79 | PTGS2 (0.48) | CA2 | |
| SCHEMBL4953176 | 0.79 | PTGS2 (0.50) | CA2 | |
| SCHEMBL4949814 | 0.77 | HPGD (0.45) | LMNAKDM4ECYP1A2CYP3A4CA2 | |
| SCHEMBL4945705 | 0.77 | SMN1; SMN2 (0.45) | LMNACYP1A2CYP3A4 | |
| SCHEMBL4957941 | 0.77 | GAA (0.39) | CYP1A2 | |
| SCHEMBL4949928 | 0.77 | ALDH1A1 (0.41) | KDM4ECYP1A2TSHR | |
| SCHEMBL4951076 | 0.77 | PTGS2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |