Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950817 | 0.88 | PTGES2 (0.42) | PTGS2PTGS1CA2CA9CA12 | |
| SCHEMBL4953413 | 0.85 | PTGS2 (0.48) | PTGS2CA2CA9ACLY | |
| SCHEMBL4951076 | 0.82 | PTGS2 (0.36) | PTGS2ACLY | |
| SCHEMBL14124478 | 0.81 | GRIA4 (0.48) | PTGS2PTGS1ACLY | |
| SCHEMBL4951303 | 0.80 | GRIA2 (0.49) | PTGS1CA2CA9CA12CA1 | |
| SCHEMBL4953693 | 0.80 | GRIA4 (0.49) | PTGS2PTGS1CA2CA9CA12 | |
| SCHEMBL4948474 | 0.79 | RORC (0.39) | CA2 | |
| SCHEMBL5141157 | 0.78 | PTGS2 (0.37) | PTGS2PTGS1CA2CA9ACLY | |
| SCHEMBL4951358 | 0.77 | ABCC4 (0.41) | PTGS1ALDH1A1 | |
| SCHEMBL27724213 | 0.76 | ACLY (0.42) | PTGS2CA2CA9ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |