Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951358 | 0.82 | ABCC4 (0.41) | GAAFFAR1ALDH1A1GRIA4 | |
| SCHEMBL4953693 | 0.81 | GRIA4 (0.49) | GRIA4 | |
| SCHEMBL4951060 | 0.81 | NPSR1 (0.44) | FFAR1ALDH1A1NPSR1 | |
| SCHEMBL4953413 | 0.80 | PTGS2 (0.48) | GRIA4 | |
| SCHEMBL4945705 | 0.80 | SMN1; SMN2 (0.45) | GAAFFAR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4949928 | 0.80 | ALDH1A1 (0.41) | GAAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4948474 | 0.77 | RORC (0.39) | CYP1A2 | |
| SCHEMBL4946259 | 0.75 | ACLY (0.45) | GAAGRIA4NPC1RAB9A | |
| SCHEMBL4949814 | 0.75 | HPGD (0.45) | GAAALDH1A1CYP1A2GRIA4NPC1 | |
| SCHEMBL4951076 | 0.75 | PTGS2 (0.36) | GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |