Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112086 | 0.85 | PGK1 (0.46) | MEN1KMT2APGK1PGK2USP2 | |
| Alafosalin SCHEMBL1582384 | 0.82 | ANPEP (0.45) | PGK1PGK2USP2TSHRANPEP | |
| SCHEMBL24670624 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2APGK1PGK2USP2 | |
| Alafosalin SCHEMBL6908702 | 0.82 | ANPEP (0.45) | PGK1PGK2USP2TSHRANPEP | |
| SCHEMBL8533026 | 0.79 | KMT2A (0.67) | MEN1KMT2AUSP2TSHRANPEP | |
| Phosphoric Acid SCHEMBL1399081 | 0.79 | MEN1 (0.56) | MEN1KMT2AUSP2TSHRANPEP | |
| SCHEMBL4949000 | 0.75 | MEN1 (0.61) | MEN1KMT2APGK1PGK2USP2 | |
| SCHEMBL1399083 | 0.75 | MEN1 (0.61) | MEN1KMT2APGK1PGK2USP2 | |
| SCHEMBL15705553 | 0.74 | PTGS1 (0.63) | MEN1KMT2APGK1PGK2USP2 | |
| SCHEMBL24138000 | 0.73 | CYP2D6 (0.46) | KMT2AUSP2TSHRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054528-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |