Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672732 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL31678747 | 0.81 | PARP1 (0.43) | CTSAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7134588 | 0.76 | TSHR (0.54) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL10547828 | 0.76 | HSPA5 (0.52) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL27255018 | 0.76 | TAAR1 (0.41) | KMT2A | |
| SCHEMBL4710690 | 0.73 | ALOX5 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29818128 | 0.73 | PARP10 (0.48) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL166483 | 0.73 | PARP10 (0.48) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL20773262 | 0.72 | EGFR (0.40) | ALDH1A1HPGDAR | |
| SCHEMBL20773600 | 0.72 | C1R (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |