SCHEMBL166483

SCHEMBL166483

NC(=O)c1ccccc1Cc1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.48
AURKA O14965 1/20 0.47
RPS6KB1 P23443 1/20 0.47
ADRA1D P25100 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
PARP1 P09874 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PTPRA P18433 1/20 0.42
HRH1 P35367 1/20 0.42
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818128 1.00 PARP10 (0.48) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
Benzamide SCHEMBL18171705 0.93 PARP10 (0.52) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL28310418 0.88 AURKA (0.46) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL6093499 0.88 AURKA (0.46) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL5792277 0.88 AURKA (0.46) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL483580 0.85 HRH1 (0.49) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL28310416 0.85 AURKA (0.44) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL11833416 0.85 ALDH1A1 (0.53) SMN1; SMN2L3MBTL1ALDH1A1HPGDKDM4E
SCHEMBL3644075 0.83 AURKA (0.50) PARP10AURKARPS6KB1ADRA1DSMN1; SMN2
SCHEMBL9366996 0.83 L3MBTL1 (0.44) PARP10SMN1; SMN2L3MBTL1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 952 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251787-A1 AGROCHEMICAL COMPOSITION, AGROCHEMICAL FORMULATION, USE OF A DIOXABICYCLOALKANE DERIVATIVE, AND, METHOD FOR THE TREATMENT AND/OR PREVENTION OF DISEASES OR PESTS IN A PLANT OR PLANT SEED OXITENO S.A. INDÚSTRIA E COMÉRCIO (BR) 2024-08-01 US claimed
CN-111372919-B Method for preparing fluopicolide 拜耳公司 2024-07-16 CN claimed
WO-2024076250-A1 A SOLID FORM FOR PREPARATION OF AN AQUEOUS DISPERSION, AQUEOUS DISPERSION, STABLE CONCENTRATE, COMBINED AQUEOUS DISPERSION, AND USES THEREOF INSIGNES LABS SP. Z O.O. (PL) 2024-04-11 WO claimed
EP-4349171-A1 A SOLID FORM FOR PREPARATION OF AN AQUEOUS DISPERSION, AQUEOUS DISPERSION, STABLE SUSPENSION CONCENTRATE, COMBINED AQUEOUS DISPERSION, AND USES THEREOF Insignes Labs Sp. z o.o. (PL) 2024-04-10 EP claimed
EP-4337008-A1 AGROCHEMICAL COMPOSITION, AGROCHEMICAL FORMULATION, USE OF A DIOXABICYCLOALKANE DERIVATIVE, AND, METHOD FOR THE TREATMENT AND/OR PREVENTION OF DISEASES OR PESTS IN A PLANT OR PLANT SEED Oxiteno S.A. Indústria e Comércio (BR) 2024-03-20 EP claimed
US-20230380418-A1 COMPOSITION, AGROCHEMICAL FORMULATION, METHODS FOR INCREASING WATER AND NUTRIENT AVAILABILITY AND FOR IMPROVING PEST CONTROL IN PLANTS AND SEEDS, AND THE AGROCHEMICAL FORMULATION OXITENO S.A. INDÚSTRIA E COMÉRCIO (BR) 2023-11-30 US claimed
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 WO claimed
EP-4229027-A1 COMPOSITION, AGROCHEMICAL FORMULATION, METHODS FOR INCREASING WATER AND NUTRIENT AVAILABILITY AND FOR IMPROVING PEST CONTROL IN PLANTS AND SEEDS, AND USES OF THE COMPOSITION AND THE AGROCHEMICAL FORMULATION Oxiteno S.A. Indústria e Comércio (BR) 2023-08-23 EP claimed
CN-116096696-A Compositions, agrochemicals, methods for increasing water and nutrient availability and improving pest control in plants and seeds, and uses of said compositions and said agrochemicals 奥克西泰诺工业和贸易公司 2023-05-09 CN claimed
CN-115251064-A Sterilization insecticidal composition and application thereof 山东省联合农药工业有限公司 2022-11-01 CN claimed
US-20040121986-A1 Fungicidal compositions BAYER CROPSCIENCE LIMITED (GB) 2004-06-24 US claimed
US-20040106578-A1 Fungicidal compositions based on pyridylmethylbenzamide derivatives and at least one complex III inhibiting compound BAYER CROPSCIENCE S.A. (FR) 2004-06-03 US claimed
EP-1372393-A1 FUNGICIDE COMPOSITIONS Bayer CropScience S.A. (FR) 2004-01-02 EP claimed
EP-1370141-A1 NOVEL FUNGICIDE COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE AND PROPAMOCARB DERIVATIVE Bayer CropScience S.A. (FR) 2003-12-17 EP claimed
EP-1365653-A1 FUNGICIDAL COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE DERIVATIVES AND AT LEAST ONE COMPLEX III INHIBITING COMPOUND Bayer CropScience S.A. (FR) 2003-12-03 EP claimed
WO-2003041501-A1 FUNGICIDAL COMPOSITION BASED ON A PYRIDYLMETHYLBENZAMIDE DERIVATIVE AND A VALINAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2003-05-22 WO claimed
WO-2003034824-A1 FUNGICIDAL COMPOSITION BASED ON AT LEAST ONE PYRIDYLMETHYLBENZAMIDE DERIVATIVE AND AT LEAST ONE DITHIOCARBAMATE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2003-05-01 WO claimed
WO-2002069713-A1 FUNGICIDE COMPOSITIONS BAYER CROPSCIENCE S.A. (FR) 2002-09-12 WO claimed
WO-2002069712-A1 FUNGICIDAL COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE DERIVATIVES AND AT LEAST ONE COMPLEX III INHIBITING COMPOUND BAYER CROPSCIENCE S.A. (FR) 2002-09-12 WO claimed
WO-2002069714-A1 NOVEL FUNGICIDE COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE AND PROPAMOCARB DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2002-09-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106578-A1 Fungicidal compositions based on pyridylmethylbenzamide derivatives and at least one complex III inhibiting compound MT-CO3, MT-CO2, COX5B PARP10 3338/4885AURKA 3701/4885RPS6KB1 1774/4885
US-20040121986-A1 Fungicidal compositions ME1, PNPO, ME3 PARP10 4564/4885AURKA 1923/4885RPS6KB1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.