Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951303 | 0.83 | GRIA2 (0.49) | PTGS1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4951505 | 0.82 | PTGS1 (0.38) | PTGS1SLC22A12GRIA1GRIA2GRIA3 | |
| SCHEMBL4949007 | 0.82 | GRM5 (0.36) | PTGS1XDHGRIA4 | |
| SCHEMBL4952472 | 0.80 | F11 (0.35) | PTGS1XDHGRIA4PTGS2 | |
| SCHEMBL4950027 | 0.79 | TDP1 (0.39) | PTGS1GRIA4ACLYPTGS2 | |
| SCHEMBL4951510 | 0.78 | PTGS1 (0.40) | PTGS1SLC22A12GRIA1GRIA2GRIA3 | |
| SCHEMBL27724208 | 0.78 | ACLY (0.42) | MCL1ACLYPTGS2 | |
| SCHEMBL4950640 | 0.78 | KDM4E (0.43) | PTGS1GRIA4ACLYPTGS2 | |
| SCHEMBL4952527 | 0.78 | PTGS2 (0.36) | PTGS1XDHPTGS2 | |
| SCHEMBL4950102 | 0.77 | PTGS1 (0.41) | PTGS1SMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |