SCHEMBL4950672

SCHEMBL4950672

C[C@@H](NS(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
POLB P06746 1/20 0.58
CA2 P00918 5/20 0.56
CA12 O43570 4/20 0.56
CA9 Q16790 4/20 0.56
MMP2 P08253 4/20 0.56
CA14 Q9ULX7 3/20 0.56
MMP1 P03956 2/20 0.56
MMP9 P14780 2/20 0.56
MMP13 P45452 2/20 0.56
MMP3 P08254 1/20 0.56
MMP7 P09237 1/20 0.56
KMT2A Q03164 3/20 0.55
LMNA P02545 2/20 0.55
MEN1 O00255 1/20 0.55
HCRTR1 O43613 1/20 0.55
MAPT P10636 1/20 0.55
CA1 P00915 3/20 0.54
CA3 P07451 1/20 0.54
CA4 P22748 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4950680 1.00 ALDH1A1 (0.62) ALDH1A1POLBCA2CA12CA9
SCHEMBL6923978 0.84 CA2 (0.59) ALDH1A1CA2CA12CA9MMP2
SCHEMBL3759433 0.84 ALDH1A1 (0.73) ALDH1A1POLBCA2CA12CA9
SCHEMBL28426090 0.84 ALDH1A1 (0.73) ALDH1A1POLBCA2CA12CA9
SCHEMBL7025505 0.83 GFER (0.54) ALDH1A1POLBCA2CA12CA9
SCHEMBL25185018 0.83 CNR1 (0.57) ALDH1A1POLBCA2CA12CA9
SCHEMBL25185020 0.83 CNR1 (0.57) ALDH1A1POLBCA2CA12CA9
Hydrochloric Acid SCHEMBL8123779 0.82 ALDH1A1 (0.71) ALDH1A1POLBCA2CA12CA9
SCHEMBL31477053 0.81 MMP9 (0.69) CA2CA12CA9MMP2CA14
SCHEMBL15658723 0.81 CRHBP (0.61) ALDH1A1POLBKMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7385064-B1 Catalysts for use in enantioselective synthesis THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2008-06-10 US disclosed