⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217762 | 0.64 | — | — | |
| SCHEMBL21389274 | 0.64 | MEN1 (0.31) | — | |
| SCHEMBL6824552 | 0.63 | MAPK1 (0.36) | — | |
| SCHEMBL21389463 | 0.62 | ALDH1A1 (0.31) | — | |
| SCHEMBL21389415 | 0.62 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL24796036 | 0.62 | ALDH1A1 (0.31) | — | |
| SCHEMBL21389465 | 0.62 | ALDH1A1 (0.31) | — | |
| SCHEMBL18289463 | 0.61 | — | — | |
| SCHEMBL14067008 | 0.60 | KMT2A (0.35) | — | |
| SCHEMBL24796253 | 0.59 | PKM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230073963-A1 | Synthesis of N-vinyl compounds by reacting cylic NH-compounds with acetylene in presence of homogenous catalyst | BASF SE (DE) | 2023-03-09 | — | — | US | disclosed |
| EP-1708765-B1 | BIOCOMPATIBLE POLYMERIZATION ACCELERATORS | SURMODICS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-8202833-B2 | Coating of polymer containing N-vinyl groups on cells, tissue | SURMODICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202833-B2 | Coating of polymer containing N-vinyl groups on cells, tissue | SURMODICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202833-B2 | Coating of polymer containing N-vinyl groups on cells, tissue | SURMODICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| EP-1708765-A2 | BIOCOMPATIBLE POLYMERIZATION ACCELERATORS | SurModics, Inc. (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005054304-A2 | BIOCOMPATIBLE POLYMERIZATION ACCELERATORS | SURMODICS, INC. (US) | 2005-06-16 | — | — | WO | disclosed |
| US-20050112086-A1 | Biocompatible polymerization accelerators | SURMODICS, INC. | 2005-05-26 | — | — | US | disclosed |