Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661024 | 0.82 | HSD17B10 (0.63) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5613007 | 0.78 | CYP2C19 (0.53) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10783918 | 0.77 | MEN1 (0.57) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5443146 | 0.76 | LMNA (0.51) | KMT2AKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL3146455 | 0.76 | HSD17B10 (0.59) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5002570 | 0.75 | ALOX5 (0.45) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28328296 | 0.75 | ALOX5 (0.52) | KMT2AKDM4EMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11726958 | 0.74 | KMT2A (0.57) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1195261 | 0.74 | MEN1 (0.57) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10783912 | 0.72 | CYP1A2 (0.55) | KMT2AKDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962838-A2 | FARNESOID X RECEPTOR AGONISTS | Smithkline Beecham Corporation (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007076260-A2 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |