Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.64 |
| ▸ | AGXT | P21549 | 2/20 | 0.64 |
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27603267 | 0.88 | CYP3A4 (0.51) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL10866481 | 0.82 | CYP3A4 (0.69) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL28404628 | 0.82 | CYP3A4 (0.69) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL1855225 | 0.80 | CYP3A4 (0.67) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL403680 | 0.78 | IDO1 (1.00) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL7040986 | 0.78 | CYP3A4 (0.64) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL13278842 | 0.78 | CYP3A4 (0.64) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL7958908 | 0.78 | CYP3A4 (0.64) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL1145772 | 0.78 | CYP3A4 (0.64) | CYP3A4IDO1AGXTPNMTMAOB | |
| SCHEMBL791970 | 0.78 | CYP3A4 (0.64) | CYP3A4IDO1AGXTPNMTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094287-A | Substituted imidazoquinolines | 生物技术公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-105612158-A | Antagonists of somatostatin receptor subtype 5 (sstr5) | TAKEDA PHARMACEUTICALS CO | 2016-05-25 | — | — | CN | disclosed |
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| CN-103079570-A | Aryl and heteroaryl sulfones as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | UNIV VANDERBILT | 2013-05-01 | — | — | CN | disclosed |
| CN-101296699-B | Pyrazolo [1,5-a ] pyrimidine compounds | MITSUBISHI TANABE PHARMA CORP | 2013-01-02 | — | — | CN | disclosed |
| CN-102196913-B | A lithographic printing plate | AGFA GRAPHICS NV | 2012-12-12 | — | — | CN | disclosed |
| CN-102333569-A | Amine or amino alcohols as glyt1 inhibitors | HOFFMANN LA ROCHE | 2012-01-25 | — | — | CN | disclosed |
| CN-102196913-A | A lithographic printing plate | AGFA GRAPHICS NV | 2011-09-21 | — | — | CN | disclosed |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| CN-101622001-A | Purine compounds and compositions as kinase inhibitors for the treatment of plasmodium related diseases | IRM LLC | 2010-01-06 | — | — | CN | disclosed |
| CN-1391473-A | VLA-4 inhibitor compounds | DAIICHI SEIYAKU CO (JP) | 2003-01-15 | — | — | CN | disclosed |
| CN-1391476-A | Vasopressin agonist formulation and process | AMERICAN CYANAMID CO (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1358174-A | New Compounds | ASTRAZENECA AB (SE) | 2002-07-10 | — | — | CN | disclosed |
| CN-1327793-A | Pyrrolo-triazine and pyrimidine compounds | DU PONT PHARM CO (US) | 2001-12-26 | — | — | CN | disclosed |
| CN-1255864-A | Combination of ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors | SEARLE & CO (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1253474-A | Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds | MONSANTO CO (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1252713-A | N-hydroxy-2-(alkyl, aryl or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID CO (US) | 2000-05-10 | — | — | CN | disclosed |
| CN-1039081-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-07-15 | — | — | CN | disclosed |
| CN-1037058-C | Herbicide composition and use thereof | RHONE POULENC AGRICULTURE (GB) | 1998-01-21 | — | — | CN | disclosed |
| CN-1026063-C | Pharmaceutical composition containing substituted thiopheno derivatives | HOECHST AG (DE) | 1994-10-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | CRYAA, ACLY, CRYZ | CYP3A4 943/4885IDO1 2510/4885AGXT 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.