Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 10/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4952642 | 0.99 | APP (0.48) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9515256 | 0.89 | APP (0.53) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL3290957 | 0.87 | APP (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL2511741 | 0.81 | KDM4E (0.57) | APPHRH3KDM4ETP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL21523588 | 0.79 | KDM4E (0.55) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL10359200 | 0.79 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9513592 | 0.79 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL15660704 | 0.79 | KDM4E (0.60) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9512074 | 0.78 | MAOB (0.48) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL12288571 | 0.77 | KDM4E (0.50) | APPHRH3KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667727-B1 | POLYAMINE-METAL CHELATOR CONJUGATES | UNIV FLORIDA (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20080096974-A2 | Polyamine-Metal Chelator Conjugates | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-20060211773-A1 | Polyamine-metal chelator conjugates | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-09-21 | — | — | US | disclosed |
| EP-1667727-A2 | POLYAMINE-METAL CHELATOR CONJUGATES | University of Florida Research Foundation, Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005023310-A2 | POLYAMINE-METAL CHELATOR CONJUGATES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211773-A1 | Polyamine-metal chelator conjugates | SLC40A1, SLC7A1, CATSPER1 | APP 3633/4885HRH3 1123/4885KDM4E 2943/4885 |
| US-20080096974-A2 | Polyamine-Metal Chelator Conjugates | SLC7A1, SLC40A1, SRM | APP 2855/4885HRH3 760/4885KDM4E 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.