Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483076 | 0.79 | TSHR (0.49) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL21319 | 0.78 | CASP6 (0.57) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL27589008 | 0.74 | CASP6 (0.53) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL7573511 | 0.74 | PDK1 (0.70) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL29886944 | 0.74 | HCAR3 (0.55) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL6892370 | 0.74 | HCAR3 (0.55) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL31378637 | 0.73 | CYP1A2 (0.38) | LMNAMEN1KMT2A | |
| SCHEMBL20214261 | 0.73 | HCAR3 (0.44) | HCAR3TSHRCASP6PDK1MEN1 | |
| SCHEMBL23752094 | 0.73 | CASP6 (0.62) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL4528943 | 0.72 | CASP6 (0.60) | HCAR3TSHRCASP6PDK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107489-A1 | APTAMER-BASED REAGENTS FOR A TARGET MOLECULE INVOLVED IN HEMOSTASIS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2008-09-12 | — | — | WO | disclosed |