Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886944 | 1.00 | HCAR3 (0.55) | HCAR3TSHRCASP6MYCMAX | |
| SCHEMBL6889360 | 0.86 | HCAR3 (0.41) | HCAR3PDK1LMNA | |
| Alcohol SCHEMBL7048031 | 0.84 | ALDH1A1 (0.40) | HCAR3PDK1LMNA | |
| SCHEMBL6892374 | 0.77 | HCAR3 (0.51) | HCAR3TSHRCASP6MYCMAX | |
| SCHEMBL21319 | 0.77 | CASP6 (0.57) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL17511817 | 0.75 | HCAR3 (0.58) | HCAR3TSHRCASP6LMNA | |
| SCHEMBL4952365 | 0.74 | HCAR3 (0.47) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL27589008 | 0.73 | CASP6 (0.53) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL7573511 | 0.73 | PDK1 (0.70) | HCAR3TSHRCASP6PDK1LMNA | |
| SCHEMBL23752094 | 0.72 | CASP6 (0.62) | HCAR3TSHRCASP6PDK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019107-A1 | REVERSIBLY INHIBITED BINDING MOLECULES | Precision Immunotherapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
| EP-4073121-A1 | REVERSIBLY INHIBITED BINDING MOLECULES | Precision Immunotherapeutics Limited (GB) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021116699-A1 | REVERSIBLY INHIBITED BINDING MOLECULES | Precision Immunotherapeutics Limited (GB) | 2021-06-17 | — | — | WO | disclosed |
| WO-2004089529-A1 | METHOD FOR THE INTRAMOLECULAR ENERGY TRANSFER FOR THE CLEAVAGE OF LABILE FUNCTIONAL GROUP FROM BIOMOLECULES AND THE PROTECTED BIOMOLECULES | Universität Konstanz (DE) | 2004-10-21 | — | — | WO | disclosed |