Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952597 | 0.77 | HSP90AB1 (0.35) | L3MBTL1CYP19A1 | |
| SCHEMBL4954850 | 0.73 | SIGMAR1 (0.35) | KCNH2SIGMAR1 | |
| SCHEMBL2000187 | 0.72 | ALOX5 (0.41) | KCNH2KDM1A | |
| SCHEMBL17482381 | 0.67 | CA2 (0.43) | L3MBTL1 | |
| SCHEMBL20857088 | 0.66 | GBA1 (0.38) | L3MBTL1 | |
| SCHEMBL22252456 | 0.65 | CA1 (0.49) | — | |
| SCHEMBL20047076 | 0.65 | CA1 (0.43) | L3MBTL1 | |
| SCHEMBL20857082 | 0.65 | RXRA (0.48) | — | |
| SCHEMBL20047001 | 0.65 | RXRA (0.41) | L3MBTL1 | |
| SCHEMBL20047046 | 0.65 | RXRA (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095292-A1 | [1,2,3] TRIAZOLYL SUBSTITUTED QUINOLINES AND COUMARINS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA LTD. (CA) | 2008-08-14 | — | — | WO | claimed |