Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180110 | 0.80 | RAPGEF4 (0.46) | TAS1R3TAS1R1TAS1R2RAPGEF4KDM4E | |
| SCHEMBL13756307 | 0.78 | RAPGEF4 (0.38) | TAS1R3TAS1R1TAS1R2RAPGEF4KDM4E | |
| SCHEMBL28949673 | 0.77 | POLB (0.44) | ALDH1A1LMNATDP1HPGD | |
| SCHEMBL6894373 | 0.76 | ALDH1A1 (0.46) | RAPGEF4KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2848308 | 0.73 | RAPGEF4 (0.43) | TAS1R3TAS1R1TAS1R2RAPGEF4KDM4E | |
| SCHEMBL21870 | 0.72 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2KDM4EL3MBTL1 | |
| SCHEMBL377596 | 0.72 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2KDM4EL3MBTL1 | |
| SCHEMBL12726829 | 0.72 | KMT2A (0.41) | RAPGEF4KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL918994 | 0.71 | RAPGEF4 (0.41) | TAS1R3TAS1R1TAS1R2RAPGEF4KDM4E | |
| SCHEMBL2722808 | 0.71 | RAPGEF4 (0.41) | TAS1R3TAS1R1TAS1R2RAPGEF4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323561-B2 | Metal complexation of 1-acyldipyrromethanes and porphyrins formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20060142562-A1 | Metal complexation of 1-acyldipyrromethanes and porphyrins formed therefrom | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142562-A1 | Metal complexation of 1-acyldipyrromethanes and porphyrins formed therefrom | AP1M1, AP3M1, DDT | TAS1R3 3909/4885TAS1R1 3915/4885TAS1R2 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.