Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42737 | 0.83 | NOS3 (0.53) | NOS3NOS1NOS2MAPT | |
| SCHEMBL11669280 | 0.81 | NOS3 (0.51) | NOS3NOS1NOS2MAPT | |
| SCHEMBL11669399 | 0.81 | NOS3 (0.51) | NOS3NOS1NOS2MAPT | |
| SCHEMBL3169716 | 0.80 | TRPA1 (0.44) | TRPA1NOS3NOS1NOS2 | |
| SCHEMBL3172309 | 0.78 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL5654987 | 0.77 | NOS3 (0.54) | NOS3NOS1NOS2MAPT | |
| SCHEMBL52608 | 0.77 | NOS3 (0.54) | NOS3NOS1NOS2MAPT | |
| SCHEMBL3173440 | 0.76 | EPHX2 (0.42) | — | |
| SCHEMBL5319456 | 0.74 | TRPA1 (0.42) | TRPA1NOS3NOS1NOS2 | |
| SCHEMBL8293176 | 0.74 | CYP19A1 (0.57) | TRPA1CYP19A1PKMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3316880-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | The Research Foundation for The State University of New York (US) | 2018-05-09 | — | — | EP | disclosed |
| WO-2017004478-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-01-05 | — | — | WO | disclosed |
| WO-2008021242-A2 | FLUOROTAXOID-FATTY ACID CONJUGATES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-21 | — | — | WO | disclosed |