Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169716 | 0.95 | TRPA1 (0.44) | TRPA1NOS3NOS1NOS2GAA | |
| SCHEMBL52608 | 0.81 | NOS3 (0.54) | NOS3NOS1NOS2 | |
| SCHEMBL5654987 | 0.81 | NOS3 (0.54) | NOS3NOS1NOS2 | |
| SCHEMBL3171548 | 0.77 | HRH3 (0.40) | IDO1 | |
| SCHEMBL42737 | 0.76 | NOS3 (0.53) | NOS3NOS1NOS2 | |
| SCHEMBL3168892 | 0.75 | ALDH1A1 (0.41) | TRPA1IDO1 | |
| SCHEMBL11669399 | 0.74 | NOS3 (0.51) | NOS3NOS1NOS2 | |
| SCHEMBL11669280 | 0.74 | NOS3 (0.51) | NOS3NOS1NOS2 | |
| SCHEMBL4953597 | 0.74 | TRPA1 (0.44) | TRPA1NOS3NOS1NOS2 | |
| SCHEMBL7379182 | 0.74 | ADRA1D (0.44) | TRPA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |