Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.60 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955184 | 0.92 | PPARG (0.58) | KCNMA1PPARGNR1H4PPARARORC | |
| SCHEMBL4952516 | 0.85 | PPARG (0.73) | PPARGNR1H4PPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL13992253 | 0.84 | KCNMA1 (0.55) | KCNMA1PPARGNR1H4PPARARORC | |
| SCHEMBL4955789 | 0.83 | PPARG (0.73) | PPARGNR1H4PPARAALDH1A1MAPT | |
| SCHEMBL4958303 | 0.83 | PPARG (0.66) | KCNMA1PPARGNR1H4PPARAALDH1A1 | |
| SCHEMBL4954952 | 0.82 | PPARG (0.65) | KCNMA1PPARGNR1H4PPARAALDH1A1 | |
| SCHEMBL4957518 | 0.80 | PPARG (0.59) | PPARGNR1H4PPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL4954313 | 0.80 | PPARG (0.67) | PPARGNR1H4PPARAALDH1A1MAPT | |
| SCHEMBL4954366 | 0.79 | PPARG (0.66) | PPARGNR1H4PPARAALDH1A1MAPT | |
| SCHEMBL4955565 | 0.79 | PPARG (0.66) | PPARGNR1H4PPARAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475776-C | Amino acid diamides in non alpha position useful as adjuvants for the administration of active biological agents | ROVI LAB FARMACEUT SA (ES) | 2009-04-08 | — | — | CN | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| EP-1652836-B1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | ROVI LAB FARMACEUT SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| EP-1652836-B1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | ROVI LAB FARMACEUT SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| CN-1829682-A | Amino acid diamides in non-alpha positions useful as adjuvants for the administration of biologically active agents | ROVI LAB FARMACEUT SA (ES) | 2006-09-06 | — | — | CN | disclosed |
| EP-1652836-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | NOS1, NOS3, ARG1 | KCNMA1 643/4885PPARG 3783/4885NR1H4 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.