Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.73 |
| ▸ | PPARA | Q07869 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | BCL3 | P20749 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30560465 | 0.87 | ABCG2 (0.63) | PPARGNR1H4PPARATP53MAPK1 | |
| SCHEMBL17554117 | 0.87 | ABCG2 (0.63) | PPARGNR1H4PPARATP53MAPK1 | |
| SCHEMBL24212364 | 0.87 | PPARG (0.80) | PPARGNR1H4PPARAALDH1A1KMT2A | |
| SCHEMBL4956471 | 0.85 | PPARG (0.60) | PPARGNR1H4PPARATP53MAPK1 | |
| SCHEMBL17554044 | 0.85 | SMN1; SMN2 (0.69) | TP53MAPK1ALDH1A1GAABCL3 | |
| SCHEMBL4957518 | 0.84 | PPARG (0.59) | PPARGNR1H4PPARATP53MAPK1 | |
| SCHEMBL4952894 | 0.84 | PPARG (0.80) | PPARGNR1H4PPARATP53MAPK1 | |
| SCHEMBL28805191 | 0.84 | ALDH1A1 (0.61) | NR1H4TP53MAPK1ALDH1A1GAA | |
| SCHEMBL2678159 | 0.84 | NPC1 (0.77) | MAPK1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL17554103 | 0.81 | ALDH1A1 (0.72) | NR1H4TP53MAPK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475776-C | Amino acid diamides in non alpha position useful as adjuvants for the administration of active biological agents | ROVI LAB FARMACEUT SA (ES) | 2009-04-08 | — | — | CN | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| EP-1652836-B1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | ROVI LAB FARMACEUT SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| EP-1652836-B1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | ROVI LAB FARMACEUT SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| CN-1829682-A | Amino acid diamides in non-alpha positions useful as adjuvants for the administration of biologically active agents | ROVI LAB FARMACEUT SA (ES) | 2006-09-06 | — | — | CN | disclosed |
| EP-1652836-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | NOS1, NOS3, ARG1 | PPARG 3783/4885NR1H4 2582/4885PPARA 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.