Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433907 | 0.69 | SRD5A2 (0.77) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| SCHEMBL40186 | 0.69 | SRD5A2 (0.77) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| SCHEMBL2155996 | 0.68 | GAA (0.38) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28119414 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL10387616 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| SCHEMBL28127726 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| SCHEMBL29208534 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL30596522 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| Fluoride SCHEMBL11120479 | 0.68 | SRD5A2 (0.74) | SRD5A2KMT2AMEN1ALDH1A1MRGPRX4 | |
| SCHEMBL29202295 | 0.67 | SRD5A2 (0.64) | SRD5A2KMT2AMEN1MRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161352-A1 | Substituted Benzo-Condensed Cycloheptanone Derivatives and the Use Thereof for Medicament Production | GRUENENTHAL GMBH (DE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161352-A1 | Substituted Benzo-Condensed Cycloheptanone Derivatives and the Use Thereof for Medicament Production | BCKDK, SYMPK, DHPS | SRD5A2 485/4885HTR7 711/4885GAA 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.