SCHEMBL495530

SCHEMBL495530

C=CC(=O)CCCCCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.63
ALDH1A1 P00352 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
PLA2G4B P0C869 7/20 0.59
RARB P10826 4/20 0.56
POLB P06746 1/20 0.56
APEX1 P27695 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PKM P14618 1/20 0.54
PLA2G4A P47712 1/20 0.54
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27894195 1.00 HTT (0.63) HTTALDH1A1L3MBTL1TP53TSHR
Hydrochloric Acid SCHEMBL7084259 0.98 HTT (0.62) HTTALDH1A1L3MBTL1TP53TSHR
SCHEMBL2107828 0.98 ALDH1A1 (0.65) HTTALDH1A1L3MBTL1TP53TSHR
Hydroquinone SCHEMBL827468 0.93 ALDH1A1 (0.58) HTTALDH1A1L3MBTL1TP53TSHR
SCHEMBL29061539 0.86 HDAC1 (0.64)
SCHEMBL5960563 0.85 HTT (0.60) HTTALDH1A1L3MBTL1TP53TSHR
SCHEMBL27853261 0.84 ALDH1A1 (0.51) HTTALDH1A1L3MBTL1TP53TSHR
SCHEMBL13183005 0.84 HDAC1 (0.61)
SCHEMBL827467 0.84 LMNA (0.51) HTTALDH1A1L3MBTL1TSHRPOLB
SCHEMBL7911508 0.83 TP53 (0.82) HTTALDH1A1L3MBTL1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device ZEON CORPORATION (JP) 2024-07-16 US disclosed
CN-110461824-B Method for producing polymerizable compound and solution 日本瑞翁株式会社 2023-09-05 CN disclosed
CN-110382471-B Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound 日本瑞翁株式会社 2023-09-01 CN disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-20220177419-A1 MULTILAYER PHASE DIFFERENCE PLATE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2022-06-09 US disclosed
CN-110392703-B Polymerizable compound and method for producing same, polymerizable composition, polymer, optical film, and optically anisotropic body 日本瑞翁株式会社 2022-02-01 CN disclosed
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2021-08-17 US disclosed
CN-110431454-B Phase difference plate, multilayer phase difference plate, polarizing plate, image display device, and polymerizable compound 日本瑞翁株式会社 2021-07-16 CN disclosed
CN-108774293-B Compound, method for producing polymerizable compound, and hydrazine compound 日本瑞翁株式会社 2021-06-04 CN disclosed
CN-1344243-A Liquid crystal compounds ROLIC AG (CH) 2002-04-10 CN disclosed
CN-1340041-A Liquid crystal compounds ROLIC AG (CH) 2002-03-13 CN disclosed
EP-1169293-A1 LIQUID CRYSTAL COMPOUNDS Rolic AG (CH) 2002-01-09 EP disclosed
EP-1154981-A1 LIQUID CRYSTAL COMPOUNDS Rolic AG (CH) 2001-11-21 EP disclosed
US-6139772-A A RADIATION POLYMERIZABLE LIQUID CRYSTAL COMPOUND COMPRISING AN INTERMOLECULAR HYDROGEN-BONDED PRODUCT OF ONE OR MORE CARBOXYLIC GROUPS AS HYDROGEN DONOR AND PYRIDINE COMPOUND AS A HYDROGEN ACCEPTOR, ONE OF WHICH HAS RADTION CURABLE GROUP JSR CORPORATION (JP) 2000-10-31 US disclosed
WO-2000055110-A1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2000-09-21 WO disclosed
WO-2000048985-A1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2000-08-24 WO disclosed
EP-0983225-A1 NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS Rolic AG (CH) 2000-03-08 EP disclosed
EP-0896047-A1 Liquid crystal composition, cured product, and manufacturing method thereof JSR Corporation (JP) 1999-02-10 EP disclosed
WO-1998052905-A1 NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS ROLIC AG (CH) 1998-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PDE8A, MAPT, PLK4 HTT 2366/4885ALDH1A1 3468/4885L3MBTL1 2549/4885
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device RAD1, RPAP1, RPA1 HTT 2827/4885ALDH1A1 4462/4885L3MBTL1 1300/4885
US-20220177419-A1 MULTILAYER PHASE DIFFERENCE PLATE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD1, RPAP1, RPA1 HTT 2826/4885ALDH1A1 4472/4885L3MBTL1 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.