Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729747 | 1.00 | KCNQ2 (0.44) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL28309576 | 0.84 | MEN1 (0.45) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL7889064 | 0.84 | KCNQ2 (0.47) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL2339105 | 0.83 | KEAP1 (0.46) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL5792889 | 0.83 | KEAP1 (0.46) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL7897470 | 0.83 | KEAP1 (0.46) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL22276693 | 0.83 | KCNQ2 (0.43) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10638555 | 0.81 | KEAP1 (0.45) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL7896588 | 0.81 | KCNQ2 (0.44) | KCNQ2GAAKEAP1MAPK1CYP1A2 | |
| SCHEMBL28304115 | 0.80 | KCNQ2 (0.44) | KCNQ2GAAKEAP1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161519-A1 | Catalyst System for Synthesizing Amine Functionalized Rubbery Polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2008-07-03 | — | — | US | claimed |
| EP-1939224-A1 | Catalyst system for synthesizing amine functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-07-02 | — | — | EP | claimed |