Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277951 | 0.86 | SMN1; SMN2 (0.43) | KCNQ2GAALMNACYP3A4ALDH1A1 | |
| SCHEMBL3729747 | 0.80 | KCNQ2 (0.44) | KCNQ2GAAABCC8MAPK1LMNA | |
| SCHEMBL7889064 | 0.80 | KCNQ2 (0.47) | KCNQ2GAAMAPK1LMNACYP3A4 | |
| SCHEMBL28309576 | 0.80 | MEN1 (0.45) | KCNQ2GAAABCC8MAPK1LMNA | |
| SCHEMBL4956719 | 0.80 | KCNQ2 (0.44) | KCNQ2GAAABCC8MAPK1LMNA | |
| SCHEMBL3633209 | 0.79 | MEN1 (0.43) | KCNQ2GAAABCC8MAPK1LMNA | |
| SCHEMBL5792889 | 0.79 | KEAP1 (0.46) | KCNQ2GAAMAPK1LMNACYP3A4 | |
| SCHEMBL2339105 | 0.79 | KEAP1 (0.46) | KCNQ2GAAMAPK1LMNACYP3A4 | |
| SCHEMBL22276693 | 0.79 | KCNQ2 (0.43) | KCNQ2GAAMAPK1LMNACYP3A4 | |
| SCHEMBL7897470 | 0.79 | KEAP1 (0.46) | KCNQ2GAAMAPK1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970681-A | A kind of synthetic method of Repaglinide | 安徽海康药业有限责任公司 | 2019-07-05 | — | — | CN | disclosed |