SCHEMBL4957452

SCHEMBL4957452

Cc1cn([C@H]2C[C@H](O)[C@@H](C(O)I)O2)c(=O)[nH]c1=O.NP(O)O

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL658884 0.94 TK1 (0.65) TK1
SCHEMBL2954289 0.87 TK1 (0.57) TK1
SCHEMBL316663 0.87 TK1 (0.65) TK1
SCHEMBL6379327 0.87 TK1 (0.67) TK1
SCHEMBL24420522 0.85 TK1 (0.65) TK1
SCHEMBL19308099 0.85 TK1 (0.65) TK1
SCHEMBL7537554 0.85 TK1 (0.65) TK1
SCHEMBL27054363 0.85 TK1 (0.65) TK1
SCHEMBL2295 0.84 TK1 (0.63) TK1
SCHEMBL3272720 0.84 TK1 (0.63) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7368560-B2 Intercalation-mediated synthesis of polymers GEORGIA TECH RESEARCH CORP. (US) 2008-05-06 US disclosed
US-20060160125-A1 Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms UNIVERSITY OF ROCHESTER (US) 2006-07-20 US disclosed
US-7033753-B1 Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms UNIVERSITY OF ROCHESTER (US) 2006-04-25 US disclosed
US-20050202459-A1 Intercalation-mediated synthesis of polymers GEORGIA TECH RESEARCH CORPORATION 2005-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050202459-A1 Intercalation-mediated synthesis of polymers ALG8, PARG, ALG1 TK1 1502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.