Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961602 | 0.93 | KIF11 (0.63) | KIF11SCN5ASCN9ACYP3A4CYP2D6 | |
| SCHEMBL4960840 | 0.79 | KIF11 (0.37) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL809990 | 0.79 | KCNN4 (0.39) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL810137 | 0.77 | KIF11 (0.57) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7661742 | 0.75 | KIF11 (0.51) | KIF11SCN5ASCN9ACYP3A4CYP2D6 | |
| SCHEMBL809896 | 0.73 | KIF11 (0.41) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4961255 | 0.71 | KCNN4 (0.41) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4959259 | 0.71 | KIF11 (0.39) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL532850 | 0.69 | KIF11 (0.61) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15051981 | 0.67 | KIF11 (0.59) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032576-B1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON ALPHA-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| US-6576684-B1 | Ammonium, phosphonium or sulfonium containing oligomers or polymers; controlled molecular weight, low polydispersity and a vinyl or dienyl end group; polymeric precursors and addi-tives | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | disclosed |
| EP-1112288-A1 | THERMAL- AND PHOTOINITIATED RADICAL POLYMERIZATION IN THE PRESENCE OF AN ADDITION FRAGMENTATION AGENT | Ciba SC Holding AG (CH) | 2001-07-04 | — | — | EP | disclosed |
| EP-1032576-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | Ciba SC Holding AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| WO-2000011041-A1 | THERMAL- AND PHOTOINITIATED RADICAL POLYMERIZATION IN THE PRESENCE OF AN ADDITION FRAGMENTATION AGENT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-02 | — | — | WO | disclosed |
| WO-1998038195-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-09-03 | — | — | WO | disclosed |