Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960840 | 0.93 | KIF11 (0.37) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4961255 | 0.78 | KCNN4 (0.41) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4961602 | 0.78 | KIF11 (0.63) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL532850 | 0.76 | KIF11 (0.61) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Water SCHEMBL28757871 | 0.74 | KIF11 (0.59) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15051981 | 0.74 | KIF11 (0.59) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL4606388 | 0.74 | KIF11 (0.59) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7667929 | 0.72 | KIF11 (0.33) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4957728 | 0.71 | KIF11 (0.59) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL809990 | 0.71 | KCNN4 (0.39) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032576-B1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON ALPHA-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| EP-1032576-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | Ciba SC Holding AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| WO-1998038195-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-09-03 | — | — | WO | disclosed |