Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 6/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364254 | 0.83 | GAA (0.57) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL4958840 | 0.83 | MEN1 (0.68) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL3932594 | 0.82 | GAA (0.70) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL7276053 | 0.80 | SIGMAR1 (0.54) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL4959051 | 0.77 | MAPT (0.53) | GAASMN1; SMN2MAPK1NPSR1L3MBTL1 | |
| SCHEMBL8252682 | 0.74 | GAA (0.68) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL64031 | 0.74 | CARM1 (0.63) | MEN1KMT2ATACR1CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL14119342 | 0.72 | MEN1 (1.00) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL30366367 | 0.72 | MEN1 (1.00) | GAASMN1; SMN2MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL21879607 | 0.72 | CARM1 (0.62) | MEN1KMT2ATACR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558610-B1 | SUBSTITUTED AMINOQUINUCLIDINE COMPOUNDS AND THEIR USE AS DELTA-OPIOID RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2008-02-27 | — | — | EP | disclosed |
| US-7179818-B2 | Substituted aminoquinuclidine compounds | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-20040110789-A1 | Substituted aminoquinuclidine compounds | BOYD ROBERT E (US) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110789-A1 | Substituted aminoquinuclidine compounds | OPRD1, OPRK1, OPRM1 | GAA 1636/4885SMN1; SMN2 4151/4885MEN1 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.