Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.60 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974400 | 1.00 | GPR35 (0.60) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL29533001 | 0.86 | GPR35 (0.59) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL70085 | 0.86 | GPR35 (0.59) | GPR35TSHRS100A4TP53HPGD | |
| SCHEMBL68675 | 0.86 | GPR35 (0.59) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL3083253 | 0.85 | GPR35 (0.71) | GPR35ERN1TSHRTP53HPGD | |
| SCHEMBL12491863 | 0.85 | GPR35 (0.57) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL12491862 | 0.85 | GPR35 (0.57) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL27469332 | 0.85 | GPR35 (0.57) | GPR35ERN1TSHRS100A4TP53 | |
| SCHEMBL472796 | 0.83 | TSHR (0.55) | GPR35TSHRS100A4SMN1; SMN2CYP3A4 | |
| SCHEMBL3683680 | 0.83 | TSHR (0.55) | GPR35TSHRSMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| CN-102070462-A | Ethylenediamine-nitrophenol type ionic liquids and preparation method thereof | INST PROCESS ENG CAS | 2011-05-25 | — | — | CN | claimed |
| CN-110612119-B | Phosphatidylether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-10-29 | — | — | CN | disclosed |
| US-20240226160-A9 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240131072-A1 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-04-25 | — | — | US | disclosed |
| EP-4291571-A2 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-117177989-A | Activity-inducible fusion proteins with heat shock protein 90 binding domain | 西雅图儿童医院以西雅图儿童研究机构名义经营 | 2023-12-05 | — | — | CN | disclosed |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | SEATTLE CHILDREN’S HOSPITAL DBA SEATTLE CHILDREN’S RES INSTITUTE (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-11649288-B2 | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | SEATTLE CHILDREN'S HOSPITAL (US) | 2023-05-16 | — | — | US | disclosed |
| US-20060236470-A1 | Novelty compositions with color changing indicator | CRAYOLA LLC | 2006-10-26 | — | — | US | disclosed |
| WO-2006105193-A2 | PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105261-A1 | CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105260-A1 | ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006105191-A2 | NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR | C2C TECHNOLOGIES LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060222675-A1 | Personal care compositions with color changing indicator | C2C TECHNOLOGIES, LLC | 2006-10-05 | — | — | US | disclosed |
| US-20060222601-A1 | Oral care compositions with color changing indicator | C2C TECHNOLOGIES, LLC | 2006-10-05 | — | — | US | disclosed |
| EP-1700896-A1 | HOT MELT ADHESIVE COMPOSITION | JSR Corporation (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-0059317-A1 | Process for the preparation of electrically conductive polymers, and use thereof | BASF Aktiengesellschaft (DE) | 1982-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060222675-A1 | Personal care compositions with color changing indicator | CUTA, POLR1C, TYR | GPR35 286/4885ERN1 4387/4885TSHR 585/4885 |
| US-11649288-B2 | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | PHOSPHO1, LCAT, CD47 | GPR35 317/4885ERN1 2928/4885TSHR 1224/4885 |
| US-20060222601-A1 | Oral care compositions with color changing indicator | CA9, CA7, TAS2R7 | GPR35 1494/4885ERN1 3985/4885TSHR 4303/4885 |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | PHOSPHO1, LCAT, CD47 | GPR35 317/4885ERN1 2928/4885TSHR 1224/4885 |
| US-20060236470-A1 | Novelty compositions with color changing indicator | MITF, CRABP2, SHH | GPR35 2712/4885ERN1 2490/4885TSHR 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.