Ethylene Glycol

Ethylene Glycol

SCHEMBL4958765

O=C(O)Cl.O=C(O)Cl.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
CAMK2A Q9UQM7 1/20 0.39
OR51E2 Q9H255 3/20 0.35
GPR84 Q9NQS5 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
LMNA P02545 2/20 0.33
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
ALDH1A1 P00352 2/20 0.31
FFAR3 O14843 1/20 0.31
GLRA1 P23415 1/20 0.31
SLC6A9 P48067 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3087642 1.00 TSHR (0.46) TSHRCAMK2AOR51E2GPR84FFAR1
Ethylene Glycol SCHEMBL9313825 1.00
Ethylene Glycol SCHEMBL5133455 0.86
Ethylene Glycol SCHEMBL27514008 0.86 TSHR (0.50) TSHRCAMK2AGPR84FFAR1FFAR4
1,4-Butanediol SCHEMBL5836779 0.84 GPR84 (0.53) TSHRCAMK2AOR51E2GPR84FFAR1
1,4-Butanediol SCHEMBL9581258 0.84 GPR84 (0.53) TSHRCAMK2AOR51E2GPR84FFAR1
1,6-Hexanediol SCHEMBL5836918 0.81 GPR84 (0.58) TSHRCAMK2AGPR84FFAR1FFAR4
Bicarbonate SCHEMBL9488228 0.80 TSHR (0.56) TSHRCAMK2AOR51E2GPR84FFAR1
Bicarbonate SCHEMBL310739 0.80
Bicarbonate SCHEMBL28880335 0.80 TSHR (0.56) TSHRCAMK2AOR51E2GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635941-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2025-10-22 EP claimed
EP-4471010-B1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INT BV (NL) 2025-06-04 EP claimed
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-12-05 US claimed
EP-4471010-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2024-12-04 EP claimed
EP-1438368-B1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2008-02-20 EP claimed
US-6998072-B2 Containing polymerizable material and photochromic compound; ophthalmic lenses TRANSITIONS OPTICAL, INC. (US) 2006-02-14 US claimed
US-6916537-B2 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL INC. (US) 2005-07-12 US claimed
EP-1451256-B1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL INC (US) 2005-06-29 EP claimed
US-20030143404-A1 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL LIMITED (IE) 2003-07-31 US claimed
US-20030136948-A1 Photochromic polymerizable compositions TRANSITIONS OPTICAL LIMITED (IE) 2003-07-24 US claimed
US-20020009599-A1 Photochromic polyurethane coating and articles having such a coating PPG INDUSTRIES OHIO, INC. 2002-01-24 US claimed
EP-4635941-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2025-10-22 EP disclosed
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US disclosed
EP-4471010-B1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INT BV (NL) 2025-06-04 EP disclosed
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-12-05 US disclosed
WO-1999032442-A1 KETONE PEROXIDE DERIVATIVES, THEIR PREPARATION AND USE AKZO NOBEL N.V. (NL) 1999-07-01 WO disclosed
US-5426190-A Preparation of N-(organocarbonyloxy)-succinimide derivatives of N-hydroxysuccinimide PPG INDUSTRIES, INC. (US) 1995-06-20 US disclosed
US-4812498-A Polycarbonate resin compositions having improved resistance to deterioration when exposed to light and containing alkylidene bis(benzotriazolyl phenols) ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-03-14 US disclosed
US-4622408-A PROTECTIVE GROUP FOR AMINO ACIDS MERCK & CO., INC. (US) 1986-11-11 US disclosed
US-3960805-A Direct synthesis of organic polymer-inorganic oxide composites TAYLOR LYNN JOHNSTON 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE GPX4, PRDX4, PRDX2 TSHR 2104/4885CAMK2A 4591/4885OR51E2 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.