Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 6/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 9/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959460 | 0.90 | MEN1 (0.41) | CCR3FAAH | |
| SCHEMBL4959675 | 0.89 | FAAH (0.39) | CCR3FAAH | |
| SCHEMBL4958786 | 0.85 | POLB (0.37) | — | |
| SCHEMBL4958259 | 0.83 | FAAH (0.41) | CCR3FAAH | |
| SCHEMBL4957412 | 0.83 | FAAH (0.47) | FAAH | |
| SCHEMBL4960982 | 0.81 | HSD11B1 (0.48) | — | |
| SCHEMBL4958536 | 0.81 | FAAH (0.41) | CYP2D6FAAH | |
| SCHEMBL4307866 | 0.81 | RIPK1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4958808 | 0.81 | SMN1; SMN2 (0.43) | CCR3FAAH | |
| SCHEMBL4958347 | 0.80 | CCR3 (0.42) | CCR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |