Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957412 | 0.88 | FAAH (0.47) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4959460 | 0.87 | MEN1 (0.41) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4958347 | 0.87 | CCR3 (0.42) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4958259 | 0.87 | FAAH (0.41) | CYP2C9CYP2C19MAPK14HTR2BMGLL | |
| SCHEMBL4958536 | 0.86 | FAAH (0.41) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4958808 | 0.84 | SMN1; SMN2 (0.43) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4959675 | 0.82 | FAAH (0.39) | CYP2C9CYP2C19MAPK14HTR2BMGLL | |
| SCHEMBL4958443 | 0.81 | POLB (0.39) | CYP2C9CYP2C19MAPK14HTR2BPRMT5 | |
| SCHEMBL4308068 | 0.81 | LIPE (0.38) | TACR1LIPECYP2C9CYP2C19MAPK14 | |
| SCHEMBL4958190 | 0.79 | MGLL (0.42) | CYP2C19MGLLKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |