SCHEMBL4959057

SCHEMBL4959057

NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACE P12821 9/20 0.40
APLNR P35414 1/20 0.39
F2 P00734 2/20 0.38
NAA50 Q9GZZ1 1/20 0.38
ACE2 Q9BYF1 2/20 0.38
NTMT1 Q9BV86 1/20 0.38
FAP Q12884 1/20 0.38
REN P00797 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28890650 0.94 APLNR (0.40) APLNRF2NAA50NTMT1FAP
SCHEMBL31544467 0.94 APLNR (0.40) APLNRF2NAA50NTMT1FAP
SCHEMBL4726312 0.94 APLNR (0.40) APLNRF2NAA50NTMT1FAP
SCHEMBL4726314 0.94 APLNR (0.40) APLNRF2NAA50NTMT1FAP
SCHEMBL31070022 0.93 APLNR (0.42) APLNRF2NAA50NTMT1FAP
SCHEMBL4258292 0.92 F2 (0.39) ACEAPLNRF2NAA50NTMT1
SCHEMBL30353946 0.91 ACE (0.41) ACEAPLNRNAA50ACE2FAP
SCHEMBL29832781 0.91 APLNR (0.38) APLNRF2NAA50NTMT1FAP
SCHEMBL29411115 0.88 ACE (0.49) ACEAPLNRF2NTMT1
SCHEMBL30563229 0.87 ACE (0.45) ACEF2ACE2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004984-A Cyclic lactam compound and liquid phase synthesis method thereof 上海瑗肽生化科技有限公司 2025-05-16 CN disclosed
CN-120004974-A Liquid phase synthesis method of cyclic lactam compound 上海瑗肽生化科技有限公司 2025-05-16 CN disclosed
CN-117384991-A Preparation method and application of high-bioactivity cyclic peptide 上海中翊日化有限公司 2024-01-12 CN disclosed
US-20080075798-A1 Personal care compositions comprising pear seed extract PROCTER & GAMBLE COMPANY, THE 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080075798-A1 Personal care compositions comprising pear seed extract CUTA, POLR1C, DPM1 ACE 2173/4885APLNR 1269/4885F2 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.