Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578169 | 0.89 | ALDH1A1 (0.32) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL31499362 | 0.77 | CYP4F2 (0.32) | MAPTCYP4F2CYP4A11 | |
| SCHEMBL31499365 | 0.77 | CYP4F2 (0.32) | MAPTCYP4F2CYP4A11 | |
| SCHEMBL3953703 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1GAA | |
| SCHEMBL998215 | 0.76 | HPGD (0.35) | PPIAHPGDCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL30415065 | 0.75 | EPHX1 (0.33) | PPIAHPGDCYP4F2CYP4A11 | |
| SCHEMBL17595509 | 0.73 | CYP4F2 (0.35) | HPGDCYP4F2CYP4A11 | |
| SCHEMBL9854762 | 0.71 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL3950941 | 0.70 | OPRK1 (0.41) | PPIAALDH1A1 | |
| SCHEMBL19281600 | 0.69 | CYP4F2 (0.35) | HPGDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874287-A2 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF OBESITY AND RELATED SYNDROMES | Innodia Inc. (CA) | 2008-01-09 | — | — | EP | disclosed |
| EP-1858840-A2 | ANALOGS OF 4-HYDROXYISOLEUCINE AND USES THEREOF | Innodia Inc. (CA) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006131836-A2 | COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF OBESITY AND RELATED SYNDROMES | INNODIA INC. (US) | 2006-12-14 | — | — | WO | disclosed |
| WO-2006120574-A2 | ANALOGS OF 4-HYDROXYISOLEUCINE AND USES THEREOF | INNODIA INC. (CA) | 2006-11-16 | — | — | WO | disclosed |