Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578169 | 0.81 | ALDH1A1 (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL3952210 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAA | |
| SCHEMBL4959664 | 0.77 | PPIA (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL5569273 | 0.72 | ACE (0.35) | KDM4ENPFFR1NPFFR2DRD2MEN1 | |
| SCHEMBL3950941 | 0.72 | OPRK1 (0.41) | ALDH1A1 | |
| SCHEMBL2084429 | 0.71 | MEN1 (0.38) | KDM4ENPFFR1NPFFR2DRD2MEN1 | |
| SCHEMBL31730515 | 0.67 | MEN1 (0.43) | NPFFR1NPFFR2DRD2MEN1KMT2A | |
| SCHEMBL18824270 | 0.66 | DRD2 (0.44) | NPFFR1NPFFR2DRD2MEN1KMT2A | |
| SCHEMBL8199704 | 0.66 | MEN1 (0.38) | NPFFR1NPFFR2DRD2MEN1KMT2A | |
| SCHEMBL2084957 | 0.66 | MEN1 (0.38) | NPFFR1NPFFR2DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888618-A4 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LTD (NZ) | 2009-07-15 | — | — | EP | disclosed |
| EP-1888618-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | Neuren Pharmaceuticals Limited (NZ) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127702-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2006-11-30 | — | — | WO | disclosed |