SCHEMBL363172

SCHEMBL363172

O=C(O)c1ccc(B(O)O)s1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.50
TSHR P16473 1/20 0.46
PKM P14618 1/20 0.45
LIG1 P18858 1/20 0.45
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
RPS6KB2 Q9UBS0 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
GAA P10253 1/20 0.39
HPGDS O60760 1/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3918796 0.80 F2 (0.54) DAOTSHRMEN1RAB9AKMT2A
SCHEMBL217943 0.80 LMNA (0.48) DAOTSHRRAB9AKDM4EALDH1A1
SCHEMBL1372080 0.79 NPSR1 (0.53) DAOTSHRRAB9AKMT2AKDM4E
SCHEMBL17212949 0.78 DAO (0.42) DAOPKMLIG1MEN1POLB
SCHEMBL1889191 0.78 DAO (0.47) DAOPKMLIG1MEN1POLB
SCHEMBL4959835 0.77 DAO (0.36) DAOTSHRPKMLIG1KMT2A
SCHEMBL70493 0.77 DAO (0.67) DAOPKMLIG1MEN1POLB
Hydrochloric Acid SCHEMBL1979156 0.75 DAO (0.64) DAOPKMLIG1MEN1POLB
SCHEMBL19987844 0.75 DAO (0.64) DAOPKMLIG1MEN1POLB
SCHEMBL11598753 0.75 DAO (0.64) DAOPKMLIG1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025231161-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-11-06 WO claimed
US-20250332181-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-10-30 US claimed
WO-2025231161-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-11-06 WO disclosed
US-20250332181-A1 ANTIBIOTIC METHODS AND COMPOSITIONS AI BIO DISCOVERY LLC (US) 2025-10-30 US disclosed
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2025-06-05 US disclosed
EP-4452918-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2024-10-30 EP disclosed
US-20240317707-A1 COVALENT AND NON-COVALENT INHIBITORS OF CORONAVIRUS PAPAIN-LIKE PROTEASE U. S. DEPARTMENT OF ENERGY 2024-09-26 US disclosed
US-20240166598-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THE SAME NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-23 US disclosed
CN-115260211-B Thiophene condensed ring derivative, pharmaceutical composition, preparation method and application thereof 长春金赛药业有限责任公司 2024-02-06 CN disclosed
WO-2023246876-A1 MEDICAL USE OF FORMAMIDE DERIVATIVES, FORMAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 上海科技大学 2023-12-28 WO disclosed
CN-117285520-A Medical use of carboxamide derivative, carboxamide derivative and pharmaceutical composition containing carboxamide derivative 上海科技大学 2023-12-26 CN disclosed
EP-1525199-A1 SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS Argenta Discovery Limited (GB) 2005-04-27 EP disclosed
WO-2005030704-A1 INHIBITORS OF HISTONE DEACETYLASE METHYLGENE, INC. (CA) 2005-04-07 WO disclosed
WO-2005014588-A1 SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY ARGENTA DISCOVERY LIMITED (GB) 2005-02-17 WO disclosed
WO-2005014588-A1 SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY ARGENTA DISCOVERY LIMITED (GB) 2005-02-17 WO disclosed
US-20050009840-A1 2-amino- pyridines and pyrazines additionally substituted witn one or more carbocyclic or heterocyclic groups, e.g., 4-[6-amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-phenol, for treating many kinds of cancer SUGEN, INC. 2005-01-13 US disclosed
US-20040220191-A1 Substituted N-aryl heterocycles, process for their preparation and their use as medicaments AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-11-04 US disclosed
WO-2004076412-A2 AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS SUGEN, INC. (US) 2004-09-10 WO disclosed
WO-2004072025-A2 SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-08-26 WO disclosed
WO-2004013130-A1 SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS ARGENTA DISCOVERY LIMITED (GB) 2004-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220191-A1 Substituted N-aryl heterocycles, process for their preparation and their use as medicaments CYP11B2, CYP11B1, CYP1A1 DAO 235/4885TSHR 3707/4885PKM 708/4885
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF GRM3, GRM2, GRM1 DAO 2316/4885TSHR 565/4885PKM 1838/4885
US-20240166598-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THE SAME SARS1, ACE, PLPBP DAO 125/4885TSHR 4501/4885PKM 1496/4885
US-20050009840-A1 2-amino- pyridines and pyrazines additionally substituted witn one or more carbocyclic or heterocyclic groups, e.g., 4-[6-amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-phenol, for treating many kinds of cancer MET, ERBB2, CDK4 DAO 344/4885TSHR 3373/4885PKM 381/4885
US-20250332181-A1 ANTIBIOTIC METHODS AND COMPOSITIONS CMBL, EBPL, BPGM DAO 18/4885TSHR 3166/4885PKM 2528/4885
US-20240317707-A1 COVALENT AND NON-COVALENT INHIBITORS OF CORONAVIRUS PAPAIN-LIKE PROTEASE HPN, CTRL, CPN1 DAO 634/4885TSHR 245/4885PKM 2801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.