Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL4962587 | 0.86 | RAB9A (0.47) | KMT2AUSP5NR4A2L3MBTL1LMNA | |
| SCHEMBL27518661 | 0.86 | USP5 (0.47) | KMT2AUSP5NR4A2L3MBTL1LMNA | |
| SCHEMBL12139296 | 0.84 | ALDH1A1 (0.45) | KMT2AL3MBTL1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4622882 | 0.83 | ALDH1A1 (0.44) | L3MBTL1LMNARAB9AALDH1A1HSD17B10 | |
| SCHEMBL4962335 | 0.82 | NR4A2 (0.47) | KMT2ANR4A2LMNACYP1A2RAB9A | |
| SCHEMBL1502354 | 0.82 | ALDH1A1 (0.43) | L3MBTL1LMNARAB9AALDH1A1HSD17B10 | |
| SCHEMBL1502465 | 0.82 | ALDH1A1 (0.43) | L3MBTL1LMNARAB9AALDH1A1HSD17B10 | |
| SCHEMBL4686360 | 0.82 | ALDH1A1 (0.43) | L3MBTL1LMNARAB9AALDH1A1HSD17B10 | |
| SCHEMBL28698668 | 0.81 | ALDH1A1 (0.47) | KMT2ALMNARAB9ASMN1; SMN2HIF1A | |
| SCHEMBL28370678 | 0.81 | GSK3B (0.54) | KMT2ALMNARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401816-B1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-7235665-B2 | Process for the production of piperidine derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20040198983-A1 | Process for the production of piperidine derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| US-6743941-B2 | INCLUDING FEXOFENADINE, USING THE CLAIMED CHEMICAL INTERMEDIATE, P-(2-CARBOXYETHYLCARBONYL)-ALPHA,ALPHA-DIMETHYLPHENYLACETIC ACID, ALKYL ESTER | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| EP-1401816-A1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | Aventis Pharma Deutschland GmbH (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030105329-A1 | Process for the production of piperidine derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-06-05 | — | — | US | disclosed |
| WO-2002102776-A1 | PROCESS FOR THE PRODUCTION OF THE PIPERIDINE DERIVATIVE FEXOFENADINE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105329-A1 | Process for the production of piperidine derivatives | HRH2, HRH1, HRH4 | KMT2A 59/4885USP5 636/4885NR4A2 1967/4885 |
| US-20040198983-A1 | Process for the production of piperidine derivatives | HRH2, HRH1, HRH4 | KMT2A 59/4885USP5 636/4885NR4A2 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.