Cadaverine Tartrate — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CHRM1 CHRM2 CHRM3 CHRM4 ESR1 ESR2 GABRA1 GABRB1 GABRG2 GBA1 HRH1 HTR1D HTR2A OPRD1 OPRK1 OPRM1 SLC6A2 SLC6A3 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	GBA1 known ✓	P04062	1/20	0.35

▸	HTR2A known ✓	P28223	3/20	0.33

▸	DRD2	P14416	7/20	0.34

▸	HTR2C	P28335	3/20	0.33

▸	HTR2B	P41595	3/20	0.33

▸	IDO1	P14902	2/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	METAP2	P50579	1/20	0.33

▸	PTPN11	Q06124	1/20	0.32

▸	STK17B	O94768	1/20	0.31

▸	STK17A	Q9UEE5	1/20	0.31

▸	CA12	O43570	1/20	0.31

▸	CA1	P00915	1/20	0.31

▸	CA2	P00918	1/20	0.31

▸	CA9	Q16790	1/20	0.31

▸	DDB1	Q16531	1/20	0.30

▸	CRBN	Q96SW2	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3965164	0.94	HTR2A (0.38)	GBA1DRD2HTR2AHTR2CHTR2B
SCHEMBL3966367	0.88	DRD2 (0.38)	DRD2HTR2AHTR2CHTR2BMEN1
SCHEMBL3961645	0.81	HTR2A (0.40)	DRD2HTR2AHTR2CHTR2B
SCHEMBL3965079	0.79	HTR2A (0.39)	HTR2AHTR2CHTR2BGAA
SCHEMBL14115742	0.76	LMNA (0.42)	DRD2HTR2AHTR2CHTR2BIDO1
SCHEMBL3965049	0.74	HTR2A (0.38)	HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL3965505	0.73	HTR2A (0.43)	DRD2HTR2AHTR2CHTR2B
SCHEMBL3970643	0.72	HTR2A (0.41)	HTR2AHTR2CHTR2BGAA
SCHEMBL30993029	0.67	CRBN (0.51)	DDB1CRBN
Cadaverine Tartrate SCHEMBL13685339	0.66	F2R (0.38)	HTR2AHTR2CHTR2BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20080207897-A1	6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[D] Azepines as 5-Ht2c Receptro Agonists	ELI LILLY AND COMPANY	2008-08-28	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20080207897-A1	6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[D] Azepines as 5-Ht2c Receptro Agonists	HTR2C, HTR2A, HTR1A	GBA1 3689/4885HTR2A 2/4885DRD2 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.