Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12061812 | 0.84 | GAA (0.66) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11562520 | 0.81 | PTGS2 (0.57) | MAPTSMN1; SMN2L3MBTL1RAB9AHPGD | |
| SCHEMBL4587997 | 0.80 | ALOX15 (0.63) | GAAMAPTSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL435444 | 0.79 | GAA (0.68) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL23605758 | 0.78 | MAPT (0.69) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11130288 | 0.78 | GAA (0.58) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10858118 | 0.78 | LMNA (0.58) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL656832 | 0.78 | LMNA (0.67) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2116437 | 0.77 | PTGS2 (0.66) | GAALMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL24844736 | 0.77 | GAA (0.76) | GAALMNAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946007-A2 | ANBROSTEEONE DERIVATIVES AND METHOD OF USE THEREOF | California Pacific Medical Center (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007048097-A2 | ANBROSTEEONE DERIVATIVES AND METHOD OF USE THEREOF | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2007-04-26 | — | — | WO | disclosed |