SCHEMBL656832

SCHEMBL656832

COc1ccc(OCC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.67
ALOX15 P16050 1/20 0.65
SMN1; SMN2 Q16637 2/20 0.63
ALDH1A1 P00352 3/20 0.60
FFAR1 O14842 2/20 0.58
TSHR P16473 1/20 0.58
NR4A1 P22736 1/20 0.58
APEX1 P27695 1/20 0.58
GAA P10253 1/20 0.58
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
PTPN7 P35236 1/20 0.56
KMT2A Q03164 1/20 0.56
PTPN12 Q05209 1/20 0.56
PPARG P37231 1/20 0.56
PPARD Q03181 1/20 0.56
PPARA Q07869 1/20 0.56
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3246059 0.98 LMNA (0.65) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL27906819 0.98 LMNA (0.65) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL10428800 0.91 LMNA (0.58) LMNAALOX15SMN1; SMN2ALDH1A1MEN1
SCHEMBL7260444 0.89 MAPT (0.75) LMNAALOX15SMN1; SMN2ALDH1A1TSHR
SCHEMBL9631701 0.89 LMNA (0.56) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL339492 0.89 ALOX15 (0.81) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL9323967 0.88 ALDH1A1 (0.59) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL7874508 0.85 ALOX15 (0.58) LMNAALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL10428819 0.83 FFAR1 (0.72) LMNAALDH1A1FFAR1GAAMEN1
SCHEMBL25623896 0.83 MAPT (0.53) LMNASMN1; SMN2ALDH1A1FFAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
WO-2024105168-A1 NOVEL COMBINATIONS USEFUL FOR THE TREATMENTS OF ALS INFLECTIS BIOSCIENCE (FR) 2024-05-23 WO claimed
EP-4076419-A1 TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS Amylyx Pharmaceuticals Inc. (US) 2022-10-26 EP claimed
CN-114929211-A Compositions of bile acid and phenylbutyric acid compounds 艾米利克斯制药公司 2022-08-19 CN claimed
CN-114929209-A Treatment of amyotrophic lateral sclerosis 艾米利克斯制药公司 2022-08-19 CN claimed
WO-2021126870-A1 COMPOSITIONS OF BILE ACIDS AND PHENYLBUTYRATE COMPOUNDS Amylyx Pharmaceuticals Inc. (US) 2021-06-24 WO claimed
WO-2021126320-A1 TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS Amylyx Pharmaceuticals Inc. (US) 2021-06-24 WO claimed
CN-112480141-A Pyranocoumarin derivative and preparation method and application thereof 吉林大学珠海学院 2021-03-12 CN claimed
EP-3750531-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2020-12-16 EP claimed
US-20200230156-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. 2020-07-23 US claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-0485587-A4 INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS 1992-12-02 EP claimed
EP-0485587-A1 INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS. BIORESEARCH INC (US) 1992-05-20 EP claimed
WO-1991018523-A1 INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS BIORESEARCH, INC. (US) 1991-12-12 WO claimed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP claimed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP claimed
EP-0021177-B1 MAYTANSINOIDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1984-02-08 EP claimed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200230156-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM LMNA 1066/4885ALOX15 532/4885SMN1; SMN2 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.