Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959706 | 0.93 | MGLL (0.46) | MGLLKMT2A | |
| SCHEMBL4958190 | 0.93 | MGLL (0.42) | HSD11B1SMN1; SMN2ALDH1A1MGLLKMT2A | |
| SCHEMBL4959344 | 0.90 | MGLL (0.46) | HSD11B1SMN1; SMN2ALDH1A1POLBMGLL | |
| SCHEMBL4959460 | 0.87 | MEN1 (0.41) | ALDH1A1POLBKMT2A | |
| SCHEMBL4958443 | 0.81 | POLB (0.39) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4957412 | 0.81 | FAAH (0.47) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4959588 | 0.81 | PSEN1 (0.38) | — | |
| SCHEMBL4958259 | 0.80 | FAAH (0.41) | ALDH1A1MGLLKMT2A | |
| SCHEMBL4310209 | 0.79 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2ALDH1A1BLMPOLB | |
| SCHEMBL4958536 | 0.79 | FAAH (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |