Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810767 | 0.81 | MEN1 (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL8604002 | 0.81 | CNR2 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL3228023 | 0.80 | CNR2 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL22777233 | 0.78 | MGAM (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL29527233 | 0.78 | MGAM (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL2020026 | 0.72 | TDP1 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28603923 | 0.71 | NR4A1 (0.68) | ALDH1A1MEN1KMT2ARAB9ACYP2C9 | |
| SCHEMBL18463776 | 0.71 | NR4A2 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9757049 | 0.70 | NR4A2 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ACNR2 | |
| SCHEMBL4961173 | 0.70 | MEN1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |