Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961177 | 0.81 | ALDH1A1 (0.46) | CNR2POLBNPC1RAB9AKMT2A | |
| SCHEMBL5816742 | 0.75 | ALDH1A1 (0.46) | SLC6A4MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL2020026 | 0.72 | TDP1 (0.33) | CNR2NR4A2NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL18463776 | 0.71 | NR4A2 (0.43) | CNR2NR4A2POLBNPC1KMT2A | |
| SCHEMBL9757049 | 0.70 | NR4A2 (0.41) | CNR2NR4A2KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9335423 | 0.70 | PRSS1 (0.38) | CNR2NR4A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8414693 | 0.70 | RAB9A (0.50) | CNR2NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5810767 | 0.69 | MEN1 (0.34) | POLBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL3228023 | 0.69 | CNR2 (0.43) | CNR2NR4A2POLBNPC1RAB9A | |
| SCHEMBL8617775 | 0.68 | MGAM (0.49) | CNR2NPC1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756518-A | EXHIBITS ANTILEUKOTRIENIC ACTION AND ANTIHISTAMINIC ACTION; IS USEFUL IN TREATMENT OF ASTHMA | KOWA CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |